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Viral hepatitis is a systematic disease with primary inflammation of the liver by one of a heterogenous group of hepatotropic viruses.
The Hepatitis viruses


The viral hepatitis is a five hepatitis : hepatitis A , hepatitis B ,hepatitis C ,hepatitis D , hepatitis E
The viral hepatitis can caued a symptoms as : herpes simplex , cytomegalovirus , epstein barr virus or even yellow fever.

•cytomegalovirus infection is caued by immunosuppressed
•epstein barr virus ( infection mononucleosis) which may cause a mild hepatitis
•yellow fever is a major symptoms in tropical countries for viral hepatitis.

Clinical signs and symptoms

1. Inflammation of liver
2.Acute viral hepatitis that is appear at less than 6 months
3. Acute hepatitis failure is a loss of a 80 to 90 % of function for liver cells
4. Chronic hepatitis is a inflammatiob of liver for at least 6 months
5.cirrhosis is replacwd normal cell liver by tissue fibrosis that lead to of liver function
6.fulminant hepatitis



Hepatitis A virus

This virus is transmitted by fecal -oral and transmitte between children and have a incubation period a 10 to 50 day ( average 25 to 30 day ) and can treated by a immunoglobulin or vaccine and type of this virus is SS RNA and approximately 40 % of all acute viral hepatitis is caused by hepatitis A virus


Transmission
•Transmitted person to person
•Ingestion of contaminated food or water
•Though direct contact with a infectious person

•Hepatitis A can be transmitted by parenteral route but very rarely by blood

Diagnosis
Specific diagnosis is made by the detection of Hepatitis A virus specific Immunogloblin M antibodies in the blood

Prevention
Hepatitis A
may be averted with the aid of using vaccination , excellent hygiene and sanitation
The vaccine protects towards HAV in extra than 95%

Treatment
Is immunogloblin and vaccines



Hepatitis B virus

This virus is transmitted by parenteral , vertical or sexual and transmitted any age and incubation period 50 to 180 day ( average 60 to 90 day ) and can treated by a immunogloblin or vaccines and types of this virus is DS DNA

Transmission
•Can transmitted by infections blood or body fluids containing blood
•Possible forms of transmission
▪︎sexual contact
▪︎ blood transfusion
▪︎reuse of syring
▪︎between family members

Diagnosis
PCR tests have been developed to detect and measure that amount of HBV DNA

Treatment
Immunogloblin and vaccines


Hepatitis C virus

This virus can transmitted by parenteral and can transmitted between adults and have a incubation period about 40 to 120 days ( average 6 to 7 weeks ) and a specific prophylaxis is nil and the type of this virus is SS RNA.

Transmission
Through contamination with the blood of another person.

Diagnosis
Hepatitis C virus antibody used to diagnosis hepatitis c infection but cases fatality rate is low and that means that HCV is chronic hepatitis only and the rate of chronic infection is 75 to 85 % and chronic hepatiti 70% and cirrhosis injure about 10% of liver and mortality from CLD
1 TO 5 % and can discovery this virus by PCR techniques

Complication of HCV if not treated
If untreated HCV can leads to confusion , disoriention , stupor , coma , jaundice , pruritus , hypothroidism , hyperthroidism

Treatment
Nil but old modalities suches interferon and ribavirin.


Hepatitis D virus

This virus can transmitted by parenteral and can injured any age and have a incubation period about 2 to 12 weeks and can treated by HBV vaccine and type of this virus is SS RNA.

Transmission
Can transmitted by broken skin or contact infected blood or blood products.

Diagnosis
HDV infection is diagnosis by high level of anti HDV immunogloblin G and immunogloblin M.

Treatment
Interferon alpha is the generally recommend treatment for hepatitis D virus infection . Treatment
must ultimate for at the least forty eight weeks regardless of the patient's response.

 


Hepatitis E virus:

This virus can transmitted by fecal -oral and can injured to young or adult andhave a incubation period about 2 to 9 weeks and specific prophylaxis is nil

Transmission
HEV can caued by transmitte fecal -oral

Diagnosis

can diagnosis by exist anti HEV immuno globlin M to the virus in person's blood and can discovered this virus by PCR


Treatment
• There
isn't anyt any precise remedy able to changing the route of acute hepatitis E
•immunogloblin suppressed people with chronic hepatitis E benefit form specific treatment using ribavirin an antiviral drug.

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